A Fast Stimulability Screening Protocol for Neuronal Cultures on Microelectrode Arrays

Kapucu, Fikret Emre ;   Tanskanen, Jarno M. A. ;   Yuting, Yuan ;   Hyttinen, Jari

Tags Neural stimulation

Microelectrode arrays (MEAs) are used to study the electrical activity in brain slices and neuronal cultures. MEA experiments for the analysis…

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Controlling Cell Migration and Adhesion into a Scaffold by External Electric Currents

Jaatinen, Leena ;   Hyttinen, Jari ;   Voros, Janos

Tags Engineered matrices for ES and stem cell maintenanceCell spreading and adhesionCell polarity and spatial patterning

Fabrication of more complex tissue-engineered structures, resembling the tissues and organs in vivo requires combining more than one cell…

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Quantifying in Vivo and in Vitro Neuronal Bursts by an Automatized Adaptive Burst Detection Algorithm and Entropy Measures

Kapucu, Fikret Emre ;   Mikkonen, Jarno Eelis ;   Tanskanen, Jarno M. A. ;   Hyttinen, Jari

Tags Neural signal processingNeural signals – Spectral analysis

In this paper, we propose employing entropy values to quantify action potential bursts in electrophysiological measurements from the brain and…

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Recurrence Network Analysis of Multiple Local Field Potential Bands from the Orofacial Portion of Primary Motor Cortex

Puthanmadam Subramaniyam, Narayan ;   Hyttinen, Jari ;   Hatsopoulos, Nicholas ;   Ross, Callum ;   Takahashi, Kazutaka

Tags Brain physiology and modelingBrain physiology and modeling – Neural dynamics and computationNeural signals – Time-frequency analysis

Local field potentials (LFPs), which have been considered as aggregate signals that reflect activities of a large number of neurons in the…

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X-Ray Microtomography of Collagen and Polylactide Scaffolds in Liquids

Hannula, Markus ;   Haaparanta, Anne-Marie ;   Tamminen, Ilmari ;   Aula, Antti ;   Kellomäki, Minna ;   Hyttinen, Jari

Tags Micro-CT

Methods to image and assess the microstructure of polymer based biomaterials in liquid phase, for example cell culture medium, are well…

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