A 3D-Continuum Bidomain Model of Retinal Electrical Stimulation using an Anatomically Detailed Mesh

Shalbaf, Farzaneh ;   Du, Peng ;   Lovell, Nigel H. ;   Dokos, Socrates ;   Vaghefi, Ehsan

Tags Biomechanics modelingMultiscale modelingCell modeling

A continuum bidomain model of sub-retinal electrical stimulation on an anatomically detailed mesh of retina is presented. The underlying…

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A Model of Electrical Stimulation of a Retinal Cell Population using a Multi-Electrode Array

Al Abed, Amr ;   Lovell, Nigel H. ;   Suaning, Gregg ;   Dokos, Socrates

Tags Medical device modelingPhysiome modelingIonic modeling

A computational modelling approach is employed to investigate the response of a population of retinal ganglion cells (RGCs) to external…

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Assistive Peripheral Prosthetic Vision Aids Perception and Mobility in Outdoor Environments: A Virtual-Reality Simulation Study

Zapf, Marc Patrick Hans ;   Boon, Mei-Ying ;   Lovell, Nigel H. ;   Suaning, Gregg

Tags Sensory neuroprostheses – VisualRehabilitation – Virtual realityNeural interfaces – Implantable systems

Retinitis pigmentosa (RP) causes visual field (VF) constriction due to progressive loss of photoreceptors, typically from the retinal periphery…

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Creating Eye Closure in Patients with Facial Nerve Paralysis using an Implantable Solenoid Actuator

Hasmat, Shaheen ;   Lovell, Nigel H. ;   Eviston, Timothy ;   Ekmejian, Rafael ;   Suaning, Gregg ;   Clark, Jonathan

Tags Prosthetic limbs, devices, and related appliances and aides

This paper proposes the use of an implantable solenoid actuator to create a more natural eyelid closure over current lid loading therapies in…

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Electrically Evoked Potentials in an Ovine Model for the Evaluation of Visual Prosthesis Efficacy

Barriga-Rivera, Alejandro ;   Eiber, Calvin D. ;   Dodds, Christopher William Douglas ;   Fung, Adrian ;   Tatarinoff, Veronica ;   Lovell, Nigel H. ;   Suaning, Gregg

Tags Sensory neuroprostheses – VisualNeural interfaces – Stimulator technology

Visual prostheses are becoming a reality as a therapy to restore functional vision to the blind. New stimulation strategies and novel…

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Electromechanics Modeling of the Effects of Myocardial Infarction on Left Ventricular Function

Leong, Chin Neng ;   Al Abed, Amr ;   Lim, Einly ;   Lovell, Nigel H. ;   Marasco, Silvana ;   Hashim, Shahrul Amry ;   Dokos, Socrates

Tags Ventricular modelsVentricular mechanicsHeart failure

Ventricular remodeling may occur following myocardial infarction of the left ventricle (LV) and such remodeling has been shown to be…

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Impact of Hierarchies of Clinical Codes on Predicting Future Days in Hospital

Xie, Yang ;   Neubauer, Sandra ;   Schreier, Guenter ;   Redmond, Stephen James ;   Lovell, Nigel H.

Tags Data miningElectronic health records

Health insurance claims contain valuable information for predicting the future health of a population. Nowadays, with many mature machine…

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Measuring Gait in Older Adults using a Single Ankle-Worn Inertial Sensor

Wang, Kejia ;   Del Rosario, Michael Benjamin ;   Hirth, Sylvain ;   Delbaere, Kim ;   Brodie, Matthew Andrew Dalhousie ;   Lovell, Nigel H. ;   Kark, Lauren ;   Lord, Stephen ;   Redmond, Stephen James

Tags Technologies for detecting, managing and preventing fallsInnovations in active ageing

This work describes the use of an ankle-worn inertial sensor to estimate the ankle trajectory through space during walking by integrating…

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Producing 3D Neuronal Networks in Hydrogels for Living Bionic Device Interfaces

Aregueta-Robles, Ulises Alejandro ;   Lim, Khoon S. ;   Martens, Penny ;   Lovell, Nigel H. ;   Poole-Warren, Laura A. ;   Green, Rylie A.

Tags Functional biomaterialsFabrication of cell seeded scaffolds

Hydrogels hold significant promise for supporting cell based therapies in the field of bioelectrodes. It has been proposed that tissue…

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Simulation of Aortic Valve Dynamics during Ventricular Support

Alonazi, Khalid ;   Lovell, Nigel H. ;   Dokos, Socrates

Tags Physiological systemsBiomechanics modelingMedical device modeling

Existing commercially-used left ventricular assist devices (LVADs) make no attempt to automatically detect the aortic valve condition in their…

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