A 3D-Continuum Bidomain Model of Retinal Electrical Stimulation using an Anatomically Detailed Mesh

Shalbaf, Farzaneh ;   Du, Peng ;   Lovell, Nigel H. ;   Dokos, Socrates ;   Vaghefi, Ehsan

Tags Biomechanics modelingMultiscale modelingCell modeling

A continuum bidomain model of sub-retinal electrical stimulation on an anatomically detailed mesh of retina is presented. The underlying…

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A Gap Junction-Based Cardiac Electromechanics Model

Ahmad Bakir, Azam ;   Dokos, Socrates

Tags Biomechanics modelingIonic modelingPhysiological systems

Action potential propagation in cardiac tissue is mainly governed by highly resistive gap junctions, which causes the tissue to behave as a…

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A Model of Electrical Stimulation of a Retinal Cell Population using a Multi-Electrode Array

Al Abed, Amr ;   Lovell, Nigel H. ;   Suaning, Gregg ;   Dokos, Socrates

Tags Medical device modelingPhysiome modelingIonic modeling

A computational modelling approach is employed to investigate the response of a population of retinal ganglion cells (RGCs) to external…

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Electromechanics Modeling of the Effects of Myocardial Infarction on Left Ventricular Function

Leong, Chin Neng ;   Al Abed, Amr ;   Lim, Einly ;   Lovell, Nigel H. ;   Marasco, Silvana ;   Hashim, Shahrul Amry ;   Dokos, Socrates

Tags Ventricular modelsVentricular mechanicsHeart failure

Ventricular remodeling may occur following myocardial infarction of the left ventricle (LV) and such remodeling has been shown to be…

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Simulation of Aortic Valve Dynamics during Ventricular Support

Alonazi, Khalid ;   Lovell, Nigel H. ;   Dokos, Socrates

Tags Physiological systemsBiomechanics modelingMedical device modeling

Existing commercially-used left ventricular assist devices (LVADs) make no attempt to automatically detect the aortic valve condition in their…

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